The efficacy of Cyracos® has been validated in a clinical study carried out on 30 volunteers.


1/ Scientific Literature and effectiveness of lemon balm against stress

The calming and anti-stress effects of lemon balm extract are acknowledged by the scientific world today.

Several studies performed on animals showed that lemon balm extract is able to reduce the restless state of the animals in a significant way. The results of these studies also record a significant reduction of the falling asleep phase, when the animals are subjected to very weak doses of sleeping drugs.

Moreover, the effectiveness of lemon balm extract was compared to other plant extracts. Results show that lemon balm extract is the most efficient against the restlessness of animals by a long shot. As an example, the figure below represents the reduction of the activity of mice supplemented with lemon balm extracts (in doses of 12 and 50 mg/kg), with passiflora or with valerian (in doses of 200 and 400 mg/kg), plants well-known for their anxiolytic properties.



Note that lemon balm is widely more active than passionflower or valerian, with distinctly lower doses.

Other studies were accomplished on humans and confirm results recorded on animals.

Further results record the following, after a supplementation of 600 mg per day of lemon balm extract:
      - significant increase of calm in the individual;
      - a significant reduction in the state of anxiety.
None of these studies reported any side effects regarding the supplementation of lemon balm extract.

In conclusion:
    - lemon balm extract is effective against the state of stress,
     - it does not affect the cognitive capacities of the studied individuals.

It is important to say that two lemon balm extracts can vary from one to another – in terms of composition, but also activity – due to the number of factors intervening in the course of their manufacture.

Furthermore, in the case of lemon balm extract, we follow a delicate manufacturing process in order to preserve all the active constituents of the plant (to find out more, click here). It appears therefore fundamental to validate the effectiveness of this extract.
This is why Naturex wanted to prove and to validate the effectiveness of Cyracos®, a natural lemon balm extract, on humans.


2/ Efficacy of Cyracos®

A clinical study accomplished on 30 persons from 18 to 70 years old scientifically showed the Antistress Action of Cyracos®: 19 parameters were measured to assess the state of general stress.

A significant reduction of the signs of anxiety is recorded on those supplemented. Moreover, Cyracos® is able to reduce in a significant manner symptoms linked to stress such as:
     - weight problems,
     - asthenia,
     - muscular contractions,
     - mental confusion,
     - guilt feelings or inferiority feelings,
     - psychosomatic disturbances.

The figure below illustrates the evolution of the various parameters studied after 15 days of supplementation.



Regarding demonstrations of anxiety, as for associated symptoms and insomnia, no significant change was noticed in the placebo group.
Finally, this study showed that supplementation in Cyracos® gave no side effects; also no drowsiness was noticed in the supplemented individual's.

Cyracos® significantly reduces the state of stress and associated symptoms without showing any side effects.

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